U-46619 for Dummies
Graphical presentation of CX-5461-mediated activation of the cytosolic DNA sensing pathway. cGAS binding on the cytosolic DNA activates the secondary messenger two,three-cGAMP making use of cGAS to be a catalyst. Activated STING buds from the ER shifting on the perinuclear Golgi, wherever it truly is palmitoylated.Meanwhile, to be sure ongoing help